CITROX

Towards a healthy mouth—The natural way

Citrox, an organic antiseptic sourced from bitter oranges, has the ability to eradicate a wide variety of bacteria, viruses and fungi, and offers advantages as a key ingredient in oral health care products.

Chlorhexidine is a key ingredient in various oral healthcare products, including mouthrinse. However, the long-term use of chlorhexidine can result in adverse side effects, such as tooth discolouration and impaired taste[i]. These issues, combined with current patient preferences, emphasise the need for innovative, new mouthrinses that consist of safe and highly effective ingredients. As a result, scientists have turned to Mother Nature in developing Citrox, which has the potential to revolutionise many industries, including dentistry.

What is Citrox?

Manufactured using naturally-derived, non-toxic, hypoallergenic and non-corrosive ingredients, Citrox is created using the bioflavonoids—plant-based compounds—found in the piths and pulp of bitter oranges, which are dried and ground into a fine powder. The powder is then mixed with other natural substances—organic acids—to produce a powerful, antimicrobial antioxidant and anti-inflammatory agent. Citrox has now been developed as a key ingredient for mouthrinses, as it has the ability to eradicate a wide variety of bacteria, viruses and fungi, making it a highly effective, natural, antimicrobial substance.

How can Citrox benefit us? 

Experts at Cardiff University believe that Citrox offers various advantages as a key ingredient in oral healthcare products, including mouthrinses. Research has revealed that Citrox is effective against dangerous pathogens, such as methicillin-resistant Staphylococcus aureus, Clostridium difficile, hepatitis A, hepatitis B and Streptococcus. According to a study by Williams, et al., Citrox, in combination with other supplements is more effective than chlorhexidine alone when it comes to protecting the oral cavity from bacteria associated with oral diseases, such as dental caries and periodontitis. This is due to the substance’s ability to deactivate a variety of micro-organisms by affecting multiple target sites, thereby surpassing traditional antibiotics that usually only target one specific area.


“Citrox, in combination with other supplements is more effective than chlorhexidine alone when it comes to protecting the oral cavity from bacteria associated with oral diseases.”

Used as a vital mouthrinse ingredient, Citrox works by breaking down bacterial biofilm quickly and efficiently to ensure a fast-acting result with long-lasting, residual effects. The strength of Citrox is evident even in the presence of organic matter and it is also less prone to bacterial resistance in that it can protect the human body against bacterial re-infiltration. This makes Citrox an extremely powerful substance that can help patients maintain good oral hygiene practices in order to reduce the risk of future complications[ii].

The organic option

Patients can also feel confident knowing that Citrox is completely biodegradable, safe to handle and eco-friendly. Since Citrox is alcohol-free and does not contain any synthetic fragrances or colourants, it does not change the flavour of food or drinks, resulting in uninterrupted taste. It also minimises the possibility of any staining on natural teeth and dental restorations, which is typical of many chlorhexidine-based mouthrinses that are currently available on the market. For additional peace of mind, Citrox is free of genetically modified organisms, it does not contain any petrochemicals or allergenic substances and it is not tested on animals, thus providing a truly natural alternative to traditional mouthwash ingredients.

Patients must be reminded of their responsibility to follow good oral hygiene routines at home. Those that suffer from acute dental problems can be particularly vulnerable, which is why using the most effective dental products is essential. By taking advantage of Citrox-based oral care solutions, patients can benefit from safe, natural protection against a host of harmful pathogens, which will enable them to ensure long-term oral health and general wellbeing.


[i] Gokul G, Lakshmanan R. Effect of chlorhexidine mouthwash on taste alteration. Asian J Pharm Clin Res. Aug 2016;9 Suppl 1:102–4.

[ii] Malic S, Emanuel C, Lewis MA, Williams DW. Antimicrobial activity of novel mouthrinses against planktonic cells and biofilms of pathogenic microorganisms. Microbiology Discovery. 2013 Oct 4;1:11.


Leave a Reply

Your email address will not be published. Required fields are marked *